BRUSSELS – The European Union has agreed to pay more than 1 billion euros ($1.2 billion) to Gilead GILD.O for a six-month supply of its antiviral drug remdesivir, shortly before the publication of final results of the biggest trial of the COVID-19 medication.

FILE PHOTO: Gilead Sciences Inc pharmaceutical company is seen after they announced a Phase 3 Trial of the investigational antiviral drug Remdesivir in patients with severe coronavirus disease (COVID-19), during the outbreak of the coronavirus disease (COVID-19), in Oceanside, California, U.S., April 29, 2020. REUTERS/Mike Blake/

The deal was agreed amid shortages in EU states, which might have hastened the decision before definitive results on whether remdesivir is as effective as so far deemed, and on its potential toxicity.

The EU signed the contract last week with the U.S. company which will allow its 27 member states and 10 partner countries, including Britain, to order up to 500,000 remdesivir courses over the next six months.

The price agreed, and previously undisclosed, for each treatment cycle is 2,070 euros ($2,440), Gilead said, for a total amount of 1 billion and 35 million euros.

Despite the big contract, the price per course is in line with that paid by EU countries in a much smaller supply deal agreed in July to treat about 30,000 patients with a six-dose course, administered in five days.

Gilead said this was the same price offered to other wealthier countries.

Solidarity has looked at four possible treatments for COVID-19: remdesivir, hydroxychloroquine, lopinavir/ritonavir, and lopanivir/ritonavir combined with interferon.

In July it discontinued trials on hydroxychloroquine and on combination HIV drug lopinavir/ritonavir after they failed to reduce mortality in hospitalised patients.

Remdesivir has been granted a conditional marketing authorisation in the EU to treat COVID-19 patients who need oxygen. The drug has so far shown no effect on milder cases and on more critical patients who need mechanical support to breathe, the EU drugs agency said.

The agency is investigating remdesivir’s potential adverse effects on kidneys.


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